Complete Genome Sequences of Highly Divergent Torque Teno Virus Type I from Swine Herds

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Complete genome sequences of highly divergent torque teno virus type I from swine herds.

Here, we report three complete genome sequences of porcine torque teno virus type I (TTV1) which were obtained from swine tissues and sera from southern China through routine and nested PCR amplification and characterized together with other genome sequences already deposited in GenBank. The results showed that the TTV1 sequences were highly divergent and could be divided into 1a and 1b subtypes.

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Anellovirus is a recently created, floating genus of viruses. Torque teno virus (TTV), the type species in the genus, was first discovered in a human patient with a post-transfusion hepatitis of unknown aetiology. Recently, TTV genetically related to but distinct from those discovered in humans have also been found in animals, including pigs. The aims of this study were to estimate the prevalen...

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Torque teno virus is a nonenveloped single-stranded DNA virus infecting humans and nonprimate species. We report the complete genome sequence of a pigeon torque teno virus isolated from pigeons in Jiangsu Province, China, in 2012. This genome sequence will be useful for viral diagnostics and disease control.

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TTV has been recently identified as a causative agent of non-A to non-G hepatitis. However, the exact role of this virus in the pathogenesis of chronic liver disease (CLD) and the development of hepatocellular carcinoma (HCC) remain controversial. To clarify these issues, the prevalence of this virus and its impact on the severity of liver disease and development of HCC among Egyptian patients ...

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Torque teno virus (TTV) is a non-enveloped human DNA virus isolated by Nishizawa et al. in 1997.1 TTV, recently classified as the Alphatorquevirus genus within the Anelloviridae family by the International Committee on Taxonomy of Viruses (ICTV), was the first human virus with a single-stranded circular DNA genome to be identified.2 Thus far, five main genetic groups (Groups 1–5) involving at l...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2012

ISSN: 0022-538X

DOI: 10.1128/jvi.02128-12